butabarbital will reduce the extent or impact of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.butabarbital will lessen the extent or result of glecaprevir/pibrentasvir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.Butabarbital belongs towards the group of medicines called barbiturates. They act in